Neuropathic Pain

Toxic Neuropathy Patient- Kimberly Neff

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KimberlyNeffKimberly Neff has Toxic Neuropathy that was caused by a work “accident”. Her story goes as this ““ Two years ago she was working as a security guard in a gate house for a residential community. When a worker from their monthly pest control company came out to spray for ants, she showed him some video footage where ants were coming from the air ducts. So, he decided to push the attic door open and just fill the attic with pesticide fog. He told her to leave both doors open, and that she should be fine: Now Kim is in a wheelchair, she can’t walk on her own, she’s lost most feeling in her legs, she sometimes loses control of her bladder and bowel functions, she has neurological problems and people treat her differently. Kim is currently on 18 different prescription medications/lotions/patches and she is still waiting on Disability for assistance.

The above has been altered from Kimberly’s own words. 

To read Kim’s entire story and consider offering assistance, please see her page at: Please help me, Toxic Neuropathy Patient

 

(This is independent of the POPF’s Patient Fundraiser for Youth)

Kim is 25 and her story touched me.

Power of Pain Patient Fundraiser Program for Youth

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POPFDONTATE-

Power of Pain Foundation is excited to announce our fundraisers program. Each month POPF will donate $200 that will be spread evenly to 4 fundraisers. Each fundraiser selected will receive a $50 dollar donation and will be hosted on the home page www.powerofpain.org With a focus on youth, each fundraiser selected must be under the age of 21.

We understand the difficulties of raising funds. We want to spread awareness about your fundraiser. We want your story to be heard and have the chance to say thank you to those that do donate. Read someones story, make a donation and feel good about yourself at the same time. No donation is too small. A whole lot of little adds up to a gob!

If you would like to donate to this program and raise the amount that gets spread evenly please click here.

Fundraisers Program

All donations are tax deductible. See your donations directly help others. When you donate to this program your donation will add to the amount that gets spread evenly amongst our fundraisers for the month. It’s a fun and exciting way to see your donation help others. When you choose to donate to this program, your name will be listed as a program sponsor. Have fun helping others and feel good about yourself at the same time.

Please make your donations to this program dividable by 4.

If you know of a youth from infant to 20 years of age, please contact:

Power of Pain’s National Youth Ambassador

Kurtis VanFleet Kurtis.CA@powerofpain.org

or Twinkle.CA@powerofpain.org

We thank you!

10th Annual Make A Wish Arizona: Walk For Wishes- (Team) Power of Pain Foundation

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POPFLogo

Please join the Power of Pain Foundation team and choose the “I Wish to BE…ORANGE” category. Orange being the awareness color for chronic neuropathy pain.

Our Team Member’s at the time of this posting are:

Barby Ingle

Our team goal is to raise $1,000. We would love to exceed that! We have raised $300 and there are 55 days left.

Please consider making a donation on my behalf on my page at:

http://www.kintera.org/i.asp?id=1074023-391201482

Or visit Power of Pain Foundation’s Page at:

and choose who you would like to donate and support.

Please know now that I may not be walking for certain as much as I would love to try. I am however raising funds for my team and the Walk For Wishes. I am still apart of the team. I’m not even 8 weeks Post Op yet and much has to do with follow up appointments and my ability to actually be able to. I still want to support and raise if I can. 🙂

Thank you for supporting Make-A-Wish Arizona. Your contribution is greatly appreciated.

Thank you also for your consideration!

Always be as well as you can be,

~Twinkle V.

Power of Pain Gets Ready for September: Pain Awareness Month

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POPFNationalPainAwarenessMonthPain Awareness Month is right around the corner.  September is always a busy time for most of us.  These are just a few of the Power of Pain Foundation’s events and activities during that time. Please feel welcome to join in on the events you are able to. We have other’s we are involved with from State to State. We look forward to all that you are doing for the mutual cause we share as well as the hope and fight for a cure we all work so hard for when raising awareness. If you have an event you would like me to share, please feel free to contact me.

I wish you pain eased days and nights, ~Twinkle V.

September is Pain Awareness Month!

PAINWeek 2013

WHEN:
September 4, 2013 – September 7, 2013

WHERE:
Cosmopolitan of Las Vegas
Las Vegas
NV
USA

CONTACT:
PAINWeek 973-415-5100
info@painweek.org
Event website: www.painweek.org

EDUCATION
Lyme MS Neuropathy Pain RSD
Audience: physicians, physician assistants, nurse practitioners, nurses, pharmacists, psychologists, hospitalists, dentists, social workers, and podiatrists

The PAINWeek 2014 Schedule at a Glance is now available! Debuting this year will be two new course formats to broaden the educational experience for our attendees:

Frontline Practitioner Focus will delve into the practice challenges that are particular to provider types and practice settings, including hospitalists, nurses, pharmacists and physician assistants
Clinical Conundrums will present case-based examinations of assessment and diagnosis, and criteria for specialist referral in the pursuit of better treatment outcomes

info@painweek.org

—————————
Chronic Pain Solutions Webinar Series
Online
CONTACT:
Power of Pain Foundation

480-882-1342

Please register for Chronic Pain Solutions on Jul 24, 2013 5:00 PM PDT at:

https://attendee.gotowebinar.com/register/7262827706450704128

Dr. Daniel Twogood, D.C., has been practicing chiropractic medicine in Southern California for 30 years. The doctor will describe 10 steps necessary to lower or eliminate chronic pain. This program does not work for everyone, but is noninvasive and we hope that attendees take away a few good pointers from it. This webinar not a cure, it is a tool to help people manage their chronic pain.

Dr. Twogood will discuss that chronic pain is caused by ongoing inflammation which is caused by specific substances in the diet, food additives & medication. He was also on the blogtalk show Living with Hope, sponsored by the Power of Pain Foundation in May 2013.

Over 100 million Americans suffer with some form of chronic pain such as back pain, fibromyalgia, migraines and arthritis.  His book is easy to read and lists the ten steps necessary to eliminate chronic conditions fibromyalgia, headaches, psoriasis, Crohn’s disease and more, based on this doctors findings over all the years he has been practicing medicine.

Where conventional medicine isn’t always effective, Dr. Daniel reports that relief is available by following these 10 steps outlined in his book. Most patients he works with recover well before 90 days.

After registering, you will receive a confirmation email containing information about joining the webinar.

The Power of Pain does not endorse the presenter or their products. This is being offered as a tool that people in pain and their caregivers can listen to, ask questions, and start a discussion.

——————–
POPF’s P.A.I.N. Summit 2013

WHEN:
September 14, 2013 @ 8:00 am – 4:00 pm

WHERE:
Scottsdale Healthcare Shea Conference Center
9003 East Shea Boulevard
Scottsdale,AZ 85260
USA
COST:
Free

ONLINE and in PERSON

CONTACT:
Power of Pain Foundation info@powerofpain.org

The 7th Annual P.A.I.N. Summit hosted by the Power of Pain Foundation provides a great avenue for pain education for providers, patients and their caregivers. This year’s conference consists of an exhibit area and educational sessions that focus on better diagnosis and treatment options for pain patients, chronic pain issues (as a whole), prescription monitoring programs, and Proper Opioid Management. There will be breakfast, lunch and afternoon snack provided to attendees.

The event will be hosted by Brittany Brannon, Miss Arizona USA 2011, model, and RSD patient. The event will also feature two celebrity speakers, Dr. Natalie Stand, MD winner of the Amazing Race, and WWE star and professional wrestler, Raven.

The day will consist of two sessions.
8am – 1:00pm The morning sessions are focused for healthcare providers. This includes all areas of expertise; anesthesiologists, complementary medicine specialists, emergency room, general practitioners, internal medicine, neurologists, nurses, orthopedics, pharmacists, physiatrists, physician assistants, primary care physicians, psychiatrists, surgeons, and therapists. Any clinician who practices, or is interested in practicing, pain management from an integrative perspective, will benefit from the meeting. HCP’s will be introduced to the rapidly expanding field of diagnosis and treatment. This conference will proved attendees a greater awareness and understanding of the need to appropriately identify, diagnose (HCPs only) and treat/seek treatment of common types of pain, including fibromyalgia, painful diabetic peripheral neuropathy and other chronic pain conditions.
1:30pm – 4:30pm The afternoon sessions will be filled with patients and their family/ caregivers. This portion of the conference will provide attendees a greater awareness and understanding of the need to appropriately identify, and treat/seek treatment of common types of pain.

There is no charge to attend this conference.
Schedule (tentative)
HCP Sessions
8:00 am – 4:00 pm Ongoing Registration Breakfast served Hosted by Brittany Brannon
8:15 am – 9:00 am Keynote address: Preventing complications that arise from diabetes such as peripheral neuropathy (pain)
Dr. Natalie Stand, MD, Amazing Race Winner, USC Pain Clinic
9:10 am – 9:55 am An Integrative Approach to Chronic Pain Dr. Philip Getson, DO, Drexel University, Philadelphia, PA
9:55 am – 10:40 am Cultural Competency and the Patient in Pain Dr. Maged Hamza, Virginia Commonwealth University
Pain Clinic Director, Richmond, VA
10:40 am – 11:20 Evidence Based Chronic Pain Care Linda Watkins, PhD, University of Colorado
11:20 am – 12:00 Complementary Medicine and its role in Chronic Pain Management (TBD)
12:00 pm – 1:00 Open Discussion with the Speakers and Attendees Lunch is served, Exhibitors

Patient/ Caregiver Sessions
1:30 pm – 2:30pm An Integrative Approach to Chronic Pain Dr. Philip Getson, DO, Drexel University, NJ
2:30 pm – 3:15 pm Prescription Drug Monitor program Explained Rob Kronenberg, PharmD
3:15 pm – 4:00pm The Patients Perspective; At Home Pain Coping Skills Raven WWE Wrestler, Barby Ingle Power of Pain
Foundation, and Diane Kennelly AZ Fibromyalgia Group Leader

If you are unable to attend in person, you can attend by watching our UStream Channel
http://www.ustream.tv/channel/power-of-pain-foundation

——————–
AANEM 60th Annual Meeting
WHEN:
September 17, 2013 – September 20, 2013

WHERE:
Montreal
QC
Canada

Event Website- http://www.aanem.org/Home.aspx

American Association of Neuromuscular & Electrodiagnostic Medicine

———————

American Academy of Pain Management

WHEN:
September 26, 2013 – September 29, 2013

WHERE:
JW Marriott Orlando
4040 Central Florida Parkway
Orlando,FL 32837
USA
CONTACT:
209-533-9744

Event Website-

http://www.aapainmanage.org/conference/annual-clinical-meeting/register.html

The American Academy of Pain Management’s 24th Annual Clinical Meeting

Come for the education, the experience, and the pure enjoyment!

Join us at the Academy’s 2013 Annual Meeting, Exploring the Science, Practicing the Art and expand your knowledge and understanding about pain management, meet some of the most forward-thinking experts in the field, gain practical hands-on experiences, and have a great time!

Who Should Attend – Any clinician who practices, or is interested in practicing, pain management from an integrative perspective, will benefit from the meeting.

—————

Institute on Psychiatric Services

WHEN:
October 10, 2013 – October 13, 2013

WHERE:
Philadelphia
PA
USA

Event Website- http://www.psych.org/

—————-

ASA Annual Meeting

WHEN:
October 12, 2013 – October 16, 2013

WHERE:
San Francisco
CA
USA

American Society of Anesthesiologists

847-825-5586

Event Website- http://www.asahq.org/

————————————-

NERVEmber

2013 Scottsdale Headache Symposium

WHEN:
November 13, 2013 – November 17, 2013

WHERE:
Scottsdale
AZ
USA

CONTACT:
American Headache Society
Event Website- http://www.achenet.org

——————-

Comic Pain Relief

WHEN:
November 8, 2013

WHERE:
Chandler Center for the Arts
250 North Arizona Avenue
Chandler,AZ 85225
USA

CONTACT:
Power of Pain Foundation 480-882-1342
info@powerofpain.org

Event Website: http://powerofpain.org/
Comic Pain Relief 2013 presented by the Power of Pain Foundation for NERVEmber. More Info to come!

Comic Pain Relief is a charity show to help raise awareness of chronic pain issues through a great social event using comedy. The event is open the public.

The Comic Pain Relief show will take place to help raise proceeds and support for low income and under-insured patients who are affected by chronic pain conditions such as Post Cancer Neuropathy, MS, Lyme Disease, Diabetic Neuropathy and Reflex Sympathetic Dystrophy.

Neuropathy pain conditions affect people of all ages, and races. There are over 100 million Americans with Chronic Pain.

KenTaylorExecutiveDirectorPowerofPainKen Taylor
Ken is the Executive Director of the Power of Pain Foundation, and an expert on several neuropathy conditions.  Ken@powerofpain.org

 

 

Through Our Motivation For a Cure, We Turn Pain Into Power!  ©powerofpain

Chronic Pain Solutions webinar presented by Power of Pain Foundation

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ChronicPainSolutionsWebinar

Chronic Pain Solutions presented by Power of Pain Foundation
Join us for a webinar on Sept. 10, 2013 at 5:00 PM PDT.

Register now!
https://attendee.gotowebinar.com/register/1513684815034504960

Dr. Daniel Twogood, D.C., has been practicing chiropractic medicine in Southern California for 30 years. The doctor will describe 10 steps necessary to lower or eliminate chronic pain. This program does not work for everyone, but is noninvasive and we hope that attendees take away a few good pointers from it. This webinar not a cure, it is a tool to help people manage their chronic pain.

Dr. Twogood will discuss that chronic pain is caused by ongoing inflammation which is caused by specific substances in the diet, food additives & medication. He was also on the backtalk show Living with Hope, sponsored by the Power of Pain Foundation in May 2013.

Over 100 million Americans suffer with some form of chronic pain such as back pain, fibromyalgia, migraines and arthritis. His book is easy to read and lists the ten steps necessary to eliminate chronic conditions fibromyalgia, headaches, psoriasis, Crohn’s disease and more, based on this doctors findings over all the years he has been practicing medicine.

Where conventional medicine isn’t always effective, Dr. Daniel reports that relief is available by following these 10 steps outlined in his book. Most patients he works with recover well before 90 days.

After registering, you will receive a confirmation email containing information about joining the webinar.

The Power of Pain does not endorse the presenter or their products. This is being offered as a tool that people in pain and their caregivers can listen to, ask questions, and start a discussion.

After registering, you will receive a confirmation email containing information about joining the webinar.

 

Chronic Pain Solutions Facebook Page- https://www.facebook.com/events/554858711238301/?ref=2

P.A.I.N.S. National Pain Management Conference hosted by Power of Pain Foundation

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P.A.I.N.Summit

  • Saturday, September 14, 2013

  • 9:00am
  		•

    Scottsdale Healthcare Shea

  • The 7th Annual P.A.I.N. Summit hosted by the Power of Pain Foundation provides a great avenue for pain education for providers, patients and their caregivers. This year’s conference consists of an exhibit area and educational sessions that focus on better diagnosis and treatment options for pain patients, chronic pain issues (as a whole), prescription monitoring programs, and Proper Opioid Management. There will be breakfast, lunch and afternoon snack provided to attendees.

     

    RSVP Required: http://painsummit2013.eventbrite.com/, Limited in-person space.

     

    The event will be hosted by Brittany Brannon, Miss Arizona USA 2011, model, and RSD patient. The event will also feature two celebrity speakers, Dr. Natalie Stand, MD winner of the

    Amazing Race, and WWE star and professional wrestler, Raven.

     

    The day will consist of two sessions.

     

    8am – 1:00pm The morning sessions are focused for healthcare providers. This includes all areas of expertise; anesthesiologists, complementary medicine specialists, emergency room, general practitioners, internal medicine, neurologists, nurses, orthopedics, pharmacists, physiatrists, physician assistants, primary care physicians, psychiatrists, surgeons, and therapists. Any clinician who practices, or is interested in practicing, pain management from an integrative perspective, will benefit from the meeting. HCP’s will be introduced to the rapidly expanding field of diagnosis and treatment. This conference will proved attendees a greater awareness and understanding of the need to appropriately identify, diagnose (HCPs only) and treat/seek treatment of common types of pain, including fibromyalgia, painful diabetic peripheral neuropathy and other chronic pain conditions.

     

    1:30pm – 4:30pm The afternoon sessions will be filled with patients and their family/ caregivers. This portion of the conference will provide attendees a greater awareness and understanding of the need to appropriately identify, and treat/seek treatment of common types of pain.

     

    There is no charge to attend this conference.

     

    Schedule (tentative)

    HCP Sessions

    8:00 am – 4:00 pm Ongoing Registration Breakfast served Hosted by Brittany Brannon

     

    8:15 am – 9:00 am Keynote address: Preventing complications that arise from diabetes such as peripheral neuropathy (pain) Dr. Natalie Stand, MD, Amazing Race Winner, USC Pain Clinic

     

    9:10 am – 9:55 am An Integrative Approach to Chronic Pain Dr. Philip Getson, DO, Drexel University, Philadelphia, PA

     

    9:55 am – 10:40 am Cultural Competency and the Patient in Pain Dr. Maged Hamza, Virginia Commonwealth University Pain Clinic Director, Richmond, VA

     

    10:40 am – 11:20 Evidence Based Chronic Pain Care Linda Watkins, PhD, University of Colorado

     

    11:20 am – 12:00 Complementary Medicine and its role in Chronic Pain Management (TBD)

     

    12:00 pm – 1:00 Open Discussion with the Speakers and Attendees Lunch is served, Exhibitors

     

    Patient/ Caregiver Sessions

    1:30 pm – 2:30pm An Integrative Approach to Chronic Pain Dr. Philip Getson, DO, Drexel University, NJ

     

    2:30 pm – 3:15 pm Prescription Drug Monitor program Explained Rob Kronenberg, PharmD

     

    3:15 pm – 4:00pm The Patients Perspective; At Home Pain Coping Skills Raven WWE Wrestler, Barby Ingle Power of Pain Foundation, and Diane Kennelly AZ Fibromyalgia Group Leader, Dr. Tory McJunkin, Arizona Pain Specialists

     

    If you are unable to attend in person, you can attend by watching our UStream Channel http://www.ustream.tv/channel/power-of-pain-foundation

Microglia- A Promising Target for Treating Neuropathic Pain

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Modulation of microglia can attenuate neuropathic pain symptoms and enhance morphine effectiveness.

Abstract

Microglia play a crucial role in the maintenance of neuronal homeostasis in the central nervous system, and microglia production of immune factors is believed to play an important role in nociceptive transmission. There is increasing evidence that uncontrolled activation of microglial cells under neuropathic pain conditions induces the release of proinflammatory cytokines (interleukin – IL-1beta, IL-6, tumor necrosis factor – TNF-alpha), complement components (C1q, C3, C4, C5, C5a) and other substances that facilitate pain transmission. Additionally, microglia activation can lead to altered activity of opioid systems and neuropathic pain is characterized by resistance to morphine. Pharmacological attenuation of glial activation represents a novel approach for controlling neuropathic pain. It has been found that propentofylline, pentoxifylline, fluorocitrate and minocycline decrease microglial activation and inhibit proinflammatory cytokines, thereby suppressing the development of neuropathic pain. The results of many studies support the idea that modulation of glial and neuroimmune activation may be a potential therapeutic mechanism for enhancement of morphine analgesia. Researchers and pharmacological companies have embarked on a new approach to the control of microglial activity, which is to search for substances that activate anti-inflammatory cytokines like IL-10. IL-10 is very interesting since it reduces allodynia and hyperalgesia by suppressing the production and activity of TNF-alpha, IL-1beta and IL-6. Some glial inhibitors, which are safe and clinically well tolerated, are potential useful agents for treatment of neuropathic pain and for the prevention of tolerance to morphine analgesia. Targeting glial activation is a clinically promising method for treatment of neuropathic pain.

Microglia: a promising target for treating neuropathic and postoperative pain, and morphine tolerance.

Source

Department of Anesthesiology, Brigham and Women’s Hospital and Harvard Medical School, Boston, MA, USA.

Abstract

Management of chronic pain, such as nerve-injury-induced neuropathic pain associated with diabetic neuropathy, viral infection, and cancer, is a real clinical challenge. Major surgeries, such as breast and thoracic surgery, leg amputation, and coronary artery bypass surgery, also lead to chronic pain in 10-50% of individuals after acute postoperative pain, partly due to surgery-induced nerve injury. Current treatments mainly focus on blocking neurotransmission in the pain pathway and have only resulted in limited success. Ironically, chronic opioid exposure might lead to paradoxical pain. Development of effective therapeutic strategies requires a better understanding of cellular mechanisms underlying the pathogenesis of neuropathic pain. Progress in pain research points to an important role of microglial cells in the development of chronic pain. Spinal cord microglia are strongly activated after nerve injury, surgical incision, and chronic opioid exposure. Increasing evidence suggests that, under all these conditions, the activated microglia not only exhibit increased expression of microglial markers CD 11 b and Iba 1, but also display elevated phosphorylation of p38 mitogen-activated protein kinase. Inhibition of spinal cord p38 has been shown to attenuate neuropathic and postoperative pain, as well as morphine-induced antinociceptive tolerance. Activation of p38 in spinal microglia results in increased synthesis and release of the neurotrophin brain-derived neurotrophic factor and the proinflammatory cytokines interleukin-1β, interleukin-6, and tumor necrosis factor-α. These microglia-released mediators can powerfully modulate spinal cord synaptic transmission, leading to increased excitability of dorsal horn neurons, that is, central sensitization, partly via suppressing inhibitory synaptic transmission. Here, we review studies that support the pronociceptive role of microglia in conditions of neuropathic and postoperative pain and opioid tolerance. We conclude that targeting microglial signaling might lead to more effective treatments for devastating chronic pain after diabetic neuropathy, viral infection, cancer, and major surgeries, partly via improving the analgesic efficacy of opioids.

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